Bioimaging of Antiangiogenic Drugs

Heparin-Like Drugs with Antiangiogenic Activity

The process of angiogenesis consists in the sprouting of new blood vessels from existing ones. This is a natural process that occurs in the human body and is essential for organ growth and repair. In the embryonic stage, the blood vessels provide the necessary oxygen, nutrients and instructive trophic signals to promote organ morphogenesis (Coultas et al., 2005). After birth the angiogenic proc...

Tyrosine Kinase Inhibitors as Antiangiogenic Drugs in Multiple Myeloma

Tyrosine kinase inhibitors are a new class of anticancer drugs, that are capable of directly interacting with the catalytic site of the target enzyme and thereby inhibiting catalysis. Therapeutically useful tyrosine kinase inhibitors are not specific for a single tyrosine kinase, but rather they are selective against a limited number of tyrosine kinases. The success of imatinib-mesylate (Gleeve...

How can we manage resistance to antiangiogenic drugs?

Nanoparticles in Bioimaging

This Special Issue of Nanomaterials is dedicated to the application of nanoparticulate materials in biological imaging.[...].

Delivery of antiangiogenic and antioxidant drugs of ophthalmic interest through a nanoporous inorganic filter.

PURPOSE We propose a novel method of administration of antiangiogenic and antioxidant drugs, with potential clinical application in the treatment of proliferative diabetic retinopathy (PDR) and age-related macular degeneration (AMD). We suggest the encapsulation of drugs in implantable sustained release devices, limited by membranes with pores in the tens of nanometers diameter range, which dis...